Lump in throat sensation expressed by patients is real and needs a thorough investigations of upper aero digestive tract. Larygopharyngeal reflux was found to be most common cause followed by emotional instability (female) & chronic granular pharyngitis. Others being sinusitis (post nasal discharge) cervical osteophytes, hypothyroidism, lingual tonsil, Larygopharygeal malignancy etc. Globus sensation can be an early sign of a malignant lesion. Hence investigations like video laryngoscopy, direct laryngoscopy, barium swallow, and esophagoscopy should be done in all patients. Psychotropic drugs have an important role in the management of these patients especially, where no organic lesions were found. Globus pharyngeus is a term which denotes a symptom rather than a diagnosis. Treatment with PPI, antidepressant / anxiolytics, saline gargles and avoidance of cold water and food items, in patients with no definite cause was found to be very effective. This combination of can be taken as an initial line of treatment until detailed evaluation and investigation results are not obtained.
Keywords: Larygopharyngeal reflux, Globus hystericus pharygus
