Neuroferritinopathy comprehensive review


Review Article

Author Details : Jitender Sharma, Anmol Sharma*

Volume : 10, Issue : 4, Year : 2024

Article Page : 182-189

https://doi.org/10.18231/j.ijn.2024.040



Suggest article by email

Get Permission

Abstract

Neuroferritinopathy is a rare, autosomal dominant neurodegenerative disorder characterized by the accumulation of iron in the brain due to mutations in the ferritin light chain gene (FTL). This article explores the incidence, prevalence, pathogenesis, types, and treatment options for neuroferritinopathy, drawing on current scientific literature to provide a comprehensive overview. Neuroferritinopathy clinically presents in mid-adulthood, most frequently between the third and the fifth decade of life. Onset: Symptoms are often gradual, though patients may develop dystonia, chorea, parkinsonism, and cognitive dysfunction.
 

Keywords: Dystonia, Movement disorder, Iron accumulation, Seizures, Chorea


How to cite : Sharma J, Sharma A, Neuroferritinopathy comprehensive review. IP Indian J Neurosci 2024;10(4):182-189


This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.







Article History

Received : 25-08-2024

Accepted : 11-11-2024


View Article

PDF File   Full Text Article


Copyright permission

Get article permission for commercial use

Downlaod

PDF File   XML File   ePub File


Digital Object Identifier (DOI)

Article DOI

https://doi.org/ 10.18231/j.ijn.2024.040


Article Metrics






Article Access statistics

Viewed: 149

PDF Downloaded: 25