Analysis of holmes tremor deep brain stimulation of ventro-intermediate thalamic nuclei and posterior subthalamic area


Original Article

Author Details : Venkateshwarla Rama Raju*

Volume : 10, Issue : 2, Year : 2024

Article Page : 87-92

https://doi.org/10.18231/j.ijn.2024.018



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Abstract

Background: Holmes tremor (HT) is rarely seen in Parkinson`s. In our recent investigation, we encountered a Parkinson patient with HT. The subject (patient) was diagnosed through HT-DBS ventro intermediate thalamic nucleus (VIM) plus posterior-sub thalamic-area (PSA) was done.
Objective: the aim was to validate our results with clinical features, etiology, outcomes as of neuroimaging, plus therapy findings in Parkinson`s.
Materials and Methods : Patient underwent numerous medications (Carbidopa, Levodopa, and mixed, benzazepines as well as tri-hexy-pheni-dyl). We applied the quantitative-techniques of Fahn-Tolosa-Marin Tremor-Rating-Scale (F.T.M.T.R.S) to measure the degree-of shaking-palsy/tremor. The scoring is a broadly utilized for measuring the tremor. The scale (measuring-tool) included the scoring-scale of the tremor site (portion A), the movement (portion B) plus functional-role (portion C). Subject scoring with F.T.M.T.R was56 plus he cannot handle the any objects, nor he sign nor scribbles nor he sign the signs nor draw the spirals-of-Archimedes. We measured the patients' Holmes tremor using F.T.M.T.R.S at 30, 90-, 180-, 365-, and 730-days following electrical stimulations via minimally invasive deep brain stimulators.
Results: On investigation, there was no improvement in symptoms reduction or restoration, increasing motor functioning restoration. There was no antiquity of consuming by means of neuroleptics and/or shaking palsy(tremor) persuading medicine in advance of or following the brain stem hemorrhage plus there was no genetic-hereditary and/or transmissible family-antiquity of the Parkinson`s disease (PD)and/or movement-disorders(MDs).
Conclusion: The outcome demonstrated that the DBS reassured the patient's tremor throughout 730-days (i.e., 24 months – 2 years) follow-up passé or retro.
 
Keywords: Deep Brain Stimulation (DBS), Electrode, HolmesTremor, Micro electrodes, Micro Electro Recording (MER), Parkinson`s disease (PD), Posterior Sub thalamic Area (PSA), Ventro intermediate thalamic nucleus (VIM)


How to cite : Raju V R, Analysis of holmes tremor deep brain stimulation of ventro-intermediate thalamic nuclei and posterior subthalamic area. IP Indian J Neurosci 2024;10(2):87-92


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Article History

Received : 16-05-2024

Accepted : 21-06-2024


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https://doi.org/10.18231/j.ijn.2024.018


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